| 摘要: |
| ［摘要］ 目的 探讨类风湿关节炎（RA）肺间质病变(RA-ILD)的发生率及相关因素。方法 对资料完整的352例住院RA患者进行回顾性分析，根据诊断分为有ILD组和无ILD组，比较分析RA-ILD发生的相关因素。结果 2005-12～2007-10住院RA患者ILD的发生率为5.1%。单因素分析相关因素为年龄、血免疫球蛋白G异常及双手X线Ⅲ/Ⅳ级改变。多因素多元逐步Logistich回归分析，相关因素为年龄和血免疫球蛋白G异常。结论 类风湿关节炎肺间质病变发生率高，是多种因素共同作用的结果。 |
| 关键词: 类风湿关节炎 肺间质病变 相关因素 |
| DOI：10.3969/j.issn.1674-3806.2012.08.11 |
| 分类号:R 593.22 |
| 基金项目: |
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| Clinical analysis on correlative factors of the rheumatoid arthritis associated interstitial lung disease |
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MO Yi,ZHAO Cheng
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Department of Rheumatology and Immunology,the First Afflicated Hospital of Guangxi Medical University，Nanning 530021，China
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| Abstract: |
| ［Abstract］ Objective To investigate the incidence and correlative factors of rheumatoid arthritis associated interstitial lung disease (RA-ILD).Methods The complete medical records of 352 in-patient with rheumatoid arthritis (RA) were retrospectively analyzed. These in-patients were divided two groups: the first group was patients with RA-ILD(RA-ILD group) and the second without RA-ILD(no ILD group). Correlative clinic factors were analyzed by the comparative method.Results The total incidence rate of RA-ILD was 5.1% in these in-patients with RA from December 2005 to October 2007. Monofactorical analysis showed that the correlative factors included age，the abnormal level of immunoglobulin G in serum and the level Ⅲ/Ⅳ damage on hand in X-ray；Multifactoical analysis indicated that the correlative factors were age and the abnormal level of immunoglobulin G in serum.Conclusion The incidence rate of RA-ILD is higher，and it is the results of multiple factors. |
| Key words: Rheumatoid arthritis(RA) Interstitial lung disease(ILD) Correlative factors |
