| 摘要: |
| ［摘要］ 缺血性中风是严重危害人类健康的疾病之一,对其防治与机制研究一直是当今医学界研究的热点之一。目前,无论是超早期溶栓治疗,还是营养脑细胞等对症治疗，都是着眼于挽救濒死的神经元，减少神经元死亡，保护神经功能。血管新生是缺血区组织抗损伤和神经元修复的结构基础，缺血性脑血管病治疗后血管新生可以促进中枢神经的再生。脑缺血后许多分子相互和谐的作用有助于脑缺血后的血管新生。研究证实,细胞膜微囊蛋白-1（Caveolin-1）在血管新生中扮演了关键的角色。该文对Caveolin-1与血管新生相关性的研究进展进行简要的综述。 |
| 关键词: Caveolae Caveolin-1 血管新生 内皮细胞 |
| DOI：10.3969/j.issn.1674-3806.2013.03.33 |
| 分类号:R 743 |
| 基金项目:湖南省中医药管理局中医药科研项目（编号：201136） |
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| The latest research of correlation between Caveolin-1 and angiogenesis |
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ZHOU De-sheng,KOU Zhi-gang,CHEN Yao,et al.
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Department of Neurology, the First Affiliated Hospital of Hunan Traditional Chinese Medicine University, Changsha 410007,China
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| Abstract: |
| ［Abstract］ Ischemic stroke is one of the diseases which is serious hazard to human health, and the research of its prevention and mechanism has been one of the hot spots of medical research today. Currently, the symptomatic treatment of both ultra-early thrombolytic therapy and nutrition brain cells are focused on rescuing dying neurons, and reducing the death of neurons, protecting the nerve function. Angiogenesis (AG) is the structure basis for resistance to damage of the organization which is lack of blood and neuron repair, and after treatment of ischemic cerebrovascular disease AG can promote central nervous system regeneration. The harmonious role of many molecules in cerebral ischemia is helpful to AG after cerebral ischemia. The research of AG confirms that the cell membrane microcapsules protein-1(Caveolin-1) plays a key role.The latest research of correlation between Caveolin-1 and angiogenesis would be summarized in this paper. |
| Key words: Caveolae Caveolin-1 Angiogenesis Endothelial cells |
