| 摘要: |
| ［摘要］ 目的 探讨降钙素原(PCT)、超敏C反应蛋白（hs-CRP)及白细胞（WBC）检测在肺部细菌感染中的诊断价值。方法 选择114例肺部感染患者，其中细菌感染63例（阳性组），非细菌感染51例（阴性组），检测两组PCT、hs-CRP、WBC水平并进行比较。结果 阳性组PCT、hs-CRP、WBC水平显著高于阴性组(P<0.01）。以0.5 ng/ml为血清PCT诊断肺部感染的截断点，得出PCT在诊断肺部细菌感染时的敏感度、特异度、准确度、阳性预测值、阴性预测值、阳性似然比、阴性似然比分别为0.921、0.882、0.904、0.906、0.900、7.825、0.090。联合检测PCT、hs-CRP和WBC水平诊断肺部细菌感染特异度高。结论 联合检测PCT、hs-CRP及WBC水平有助于肺部细菌感染的诊断与鉴别诊断。 |
| 关键词: 降钙素原 超敏C反应蛋白 白细胞计数 肺部细菌感染 |
| DOI：10.3969/j.issn.1674-3806.2015.02.12 |
| 分类号:R 563.1 |
| 基金项目: |
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| Value of procalcitonin, hypersensitive C-reactive protein and white blood cells count in diagnosis of pulmonary bacterial infection |
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LIU Hua-xiang,YUE Feng, WU Tao
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Department of Clinical Laboratory, Beifang Hospital, Huainan Panji Xinhua Medical Group, Anhui 232082, China
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| Abstract: |
| ［Abstract］ Objective To explore the value of procalcitonin(PCT),hypersensitive C-reactive protein(hs-CRP) and white blood cell(WBC) in the diagnosis for pulmonary bacterial infection.Methods One hundred and fourteen patients with pulmonary infection were chosed in this study and were divided into two groups:positive group(sixty-three patients with bacterial infection),negative group(fifty-one patients with non bacterial infection).The levels of serum PCT, hs-CRP and the periphal WBC were detected and compared in the two groups.Results The levels of serum PCT,hs-CRP and WBC in bacterial infection group were significantly higher than those in non bacterial infection group.The cut-off point of serum PCT in the diagnosis of pulmonary bacterial infection was 0.5 ng/ml. Based on this,the sensitivity,specificity, accuracy,positive predictive value,negative predictive value,positive likelihood ratio and negative likelihood ratio were 0.921,0.882,0.904,0.906,0.900,7.825 and 0.090 respectively. The specificity of combined detection of PCT, hs-CRP and WBC levels in the diagnosis of pulmonary infection was high.Conclusion The combined detection of PCT， hs-CRP and WBC levels is helpful in the diagnosis and differential diagnosis for pulmonary bacterial infection. |
| Key words: Procalcitonin Hypersensitive C-reactive protein(hs-CRP) White blood cells count Pulmonary bacterial infection |
