| 摘要: |
| ［摘要］ 目的 了解2010～2014年该院多重耐药菌感染现状及其耐药情况。方法 回顾统计分析该院2010～2014年多重耐药菌检出率及其耐药性。结果 耐甲氧西林金黄色葡萄球菌（MRSA）检出率从2010年13.1%上升至2014年40.7%，呈逐年线性上升趋势（P=0.000）；耐碳青霉烯类肠杆菌（CRE）检出率从2010年0.8%上升至2014年2.2%，基本呈逐年线性上升趋势（P=0.003）；耐碳青霉烯铜绿假单胞菌（CRPAE）各年检出率变化不大，各年检出率差异无统计学意义（P=0.350）；耐碳青霉烯鲍曼不动杆菌（CRABA）各年检出率差异较大（P=0.000）。对CRABA、CRPAE、MRSA不同年度耐药率分析，仅CRABA对氨苄西林/舒巴坦、米诺环素、头孢哌酮/舒巴坦、左氧氟沙星耐药率差异有统计学意义，其他常用抗菌药物和CRPAE耐药率变化差异无统计学意义。MRSA不同年度耐药率对10种药物分析差异无统计学意义。结论 MRSA、CRE检出率逐年上升,CRPAE各年度检出率变化不大,CRABA检出率各年间起伏不定，差异较大。常用抗菌药物对多种多重耐药菌的耐药率无明显变化。 |
| 关键词: 多重耐药菌 检出率 耐药性 |
| DOI：10.3969/j.issn.1674-3806.2016.07.26 |
| 分类号:R 446 |
| 基金项目:广西卫计委科研课题（编号：Z2015492） |
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| Analysis on the detective rate and drug resistance of bacteria in a county hospital of Guangxi |
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LI Ri-hai, LIU Jian-yu, WU Jia-wen
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The People′s Hospital of Guiping City, Guangxi 537200, China
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| Abstract: |
| ［Abstract］ Objective To explore the distribution and drug resistance of bacteria in our hospital from 2010 to 2014.Methods The detective rate and resistance of bacteria in our hospital from 2010 to 2014 were retrospectively analyzed.Results The detective rates of methicillin resistant staphylococcus aureus(MRSA) were increased from 13.1% in 2010 to 40.7% in 2014, with a linearly increased trend year by year(P=0.000). From 2010 to 2014, the detective rates of carbapenem resistant enterobacteriaceae(CRE) were increased linearly from 0.8% to 2.2%(P=0.003). There were no significant differences in the detective rates of carbapenem resistant pseudomonas aeruginosa(CRPAE) among the four years(P=0.350). The detective rates of carbapenem resistant acinetobacter baumannii(CRABA) were fluctuated greatly during the four years(P=0.000). By analyzing the drug resistance in different years except for the resistance rates of minocycline, cefoperazone/sulbactam and levofloxacin to CRABA, there were no significant differences in the resistance rates of the other commonly used antibacterials to CRABA, CRPAE and MRSA.Conclusion The detective rates of MRSA and CRE increase year by year, however little change is showed in the detective rates of CRPAE from year to year.The detective rates of CRABA are fluctuated greatly from 2010 to 2014. There are not obvious changes in the resistance rates of the commonly used antibacterials to the muti-drug resistant bacteria. |
| Key words: Multi-drug resistant bacteria Detective rate Drug resistance |
